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Gregory G Freund Selected Research

N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone

10/2012Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1.
1/2007Acute hypoxia activates the neuroimmune system, which diabetes exacerbates.

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Gregory G Freund Research Topics

Disease

8Type 2 Diabetes Mellitus (MODY)
01/2016 - 07/2004
6Obesity
01/2018 - 09/2006
6Hypoxia (Hypoxemia)
10/2012 - 01/2007
5Neoplasms (Cancer)
01/2018 - 08/2002
5Infections
05/2013 - 01/2008
3Inflammation (Inflammations)
01/2018 - 01/2008
3Alzheimer Disease (Alzheimer's Disease)
12/2014 - 09/2006
2Overnutrition
01/2018 - 09/2013
2Sepsis (Septicemia)
08/2013 - 05/2008
2Cardiovascular Diseases (Cardiovascular Disease)
08/2012 - 05/2008
2Fatigue
02/2012 - 06/2008
2Hypoglycemia (Reactive Hypoglycemia)
02/2012 - 11/2008
2Hyperglycemia
08/2007 - 01/2007
2Breast Neoplasms (Breast Cancer)
06/2004 - 08/2002
2Retinoblastoma (Glioblastoma, Retinal)
06/2004 - 02/2004
1Needlestick Injuries (Needlestick Injury)
01/2019
1Seizures (Absence Seizure)
01/2019
1Lung Diseases (Lung Disease)
01/2018
1Fatty Liver
01/2018
1Virus Diseases (Viral Diseases)
01/2017
1Human Influenza (Influenza)
01/2017
1Cognitive Dysfunction
01/2016
1Mental Disorders (Mental Disorder)
12/2014
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
12/2014
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
09/2013
1Weight Gain
09/2013
1Labyrinth Diseases
08/2013
1Arthritis (Polyarthritis)
08/2013
1Atherosclerosis
08/2013
1Ulcerative Colitis
08/2013
1Endometriosis
08/2013
1Neuroinflammatory Diseases
05/2013
1Brain Injuries (Brain Injury)
10/2012
1Anterograde Amnesia
10/2012
1Colonic Neoplasms (Colon Cancer)
08/2012
1AIDS-Related Complex (ARC)
02/2012
1Lethargy
06/2008

Drug/Important Bio-Agent (IBA)

9CytokinesIBA
01/2019 - 08/2002
5Insulin (Novolin)FDA Link
02/2012 - 07/2004
4Glucose (Dextrose)FDA LinkGeneric
01/2018 - 07/2004
4Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
02/2012 - 01/2007
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2008 - 02/2004
4Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
06/2007 - 06/2004
3Proteins (Proteins, Gene)FDA Link
01/2018 - 06/2004
3Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
10/2012 - 02/2009
3Biological ProductsIBA
08/2012 - 08/2002
2Dietary FiberFDA Link
01/2018 - 08/2012
2Adenosine (Adenocard)FDA LinkGeneric
12/2014 - 10/2012
2InterleukinsIBA
05/2013 - 02/2009
2N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketoneIBA
10/2012 - 01/2007
2Insulin ReceptorIBA
06/2007 - 07/2004
2Interleukin-4 (Interleukin 4)IBA
06/2007 - 07/2004
2Phosphotransferases (Kinase)IBA
01/2007 - 09/2006
2TOR Serine-Threonine KinasesIBA
07/2004 - 06/2004
2Cyclin AIBA
06/2004 - 02/2004
2Insulin-Like Growth Factor I (IGF-1)IBA
06/2004 - 02/2004
1salicylhydroxamic acid (SHAM)IBA
01/2019
1KynurenineIBA
01/2019
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
01/2019
1PectinsIBA
01/2018
1CelluloseIBA
01/2018
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2017
1Glyburide (Glibenclamide)FDA LinkGeneric
01/2016
1Adenosine Triphosphate (ATP)IBA
01/2016
1Anti-Anxiety Agents (Anxiolytics)IBA
01/2016
1KATP ChannelsIBA
01/2016
1Hemostatics (Antihemorrhagics)IBA
12/2014
1FatsIBA
09/2013
1Dopamine (Intropin)FDA LinkGeneric
09/2013
1Interleukin-6 (Interleukin 6)IBA
05/2013
1Cytokine Receptor gp130IBA
05/2013
1Caspase 1 (ICE Protease)IBA
10/2012
1Caffeine (No Doz)FDA LinkGeneric
10/2012
1Interleukin-1 (Interleukin 1)IBA
10/2012
1Oxygen (Dioxygen)IBA
08/2012
1SaccharinIBA
02/2012
1Antidepressive Agents (Antidepressants)IBA
02/2012
1Butoxamine (Butaxamine)IBA
02/2012
1Desipramine (Pertofrane)FDA LinkGeneric
02/2012
1Fluoxetine (Prozac)FDA LinkGeneric
02/2012
1Hypoglycemic Agents (Hypoglycemics)IBA
02/2012
1Metoprolol (Toprol-XL)FDA LinkGeneric
02/2012
1Phentolamine (Z-Max)FDA LinkGeneric
02/2012
1Adrenergic Agents (Adrenergic Drugs)IBA
02/2012
1Adrenergic Antagonists (Antiadrenergic Agents)IBA
02/2012
1Dexfenfluramine (Redux)IBA
05/2009
1Leptin ReceptorsIBA
02/2009
1LeptinIBA
02/2009
1CatecholaminesIBA
11/2008
1Blood Glucose (Blood Sugar)IBA
11/2008
1beta-2 Adrenergic ReceptorsIBA
11/2008
1Messenger RNA (mRNA)IBA
03/2008
1LipopolysaccharidesIBA
03/2008
1interleukin-1beta-converting enzyme inhibitorIBA
01/2007
1Myeloid Differentiation Factor 88IBA
01/2007
1JNK Mitogen-Activated Protein KinasesIBA
09/2006

Therapy/Procedure

1Caloric Restriction
01/2018
1Organ Transplantation
08/2013
1Radiotherapy
02/2012
1Lasers (Laser)
03/2008